Mayo Clinic College of Medicine and Science Rochester Program

Program Identity & Fit

Mayo Clinic's Clinical Medical Genetics Residency is a two-year (optional third-year) ACGME-accredited program embedded in a quaternary academic referral center, drawing regional, national, and international patients across the full genetic disease spectrum—monogenic, chromosomal, mitochondrial, multifactorial, and teratogenic—with a notably adult-heavy population (roughly half of clinic patients) that distinguishes it from pediatrics-dominated genetics programs. The curriculum integrates dedicated laboratory rotations (cytogenetics, biochemical, molecular), prenatal and cancer/cardiology genetics with counselors, and a Center for Individualized Medicine rotation, reflecting deep infrastructure linking clinical genetics to genomic and laboratory medicine. Research is encouraged rather than mandatory, with a Clinical Investigator Track and structured presentation opportunities, while the optional third year enables board eligibility in biochemical or laboratory genetics and genomics, signaling a program built to produce both clinician-consultants and lab-oriented subspecialists. The program explicitly states graduates go on to private practice or academic medicine, and notes Mayo often hires its own trainees into staff positions, underscoring an institutional-loyalty and long-term career-building orientation.