Greenwood Genetic Center Program

Program Identity & Fit

The Greenwood Genetic Center Program is a freestanding, nonprofit medical genetics institute (not a traditional academic medical center) that trains Clinical Genetics residents within an integrated model spanning statewide clinical genetics clinics, an in-house diagnostic laboratory, and an active JC Self Research Institute, with a formal partnership with MUSC. Its patient base centers on rare and undiagnosed genetic disorders, congenital disorders of glycosylation, lysosomal storage disorders, inherited retinal disease, and metabolic conditions, served through both in-person and telegenetics clinics across South Carolina. Research is deeply embedded in daily practice - residents/fellows train alongside PhD scientists conducting functional studies, model-organism work, and drug-repurposing efforts aimed at translating variants of uncertain significance into actionable diagnoses - and the program's outcomes show virtually all graduates going on to direct diagnostic laboratories. The program requires prior completion of a three-year primary care residency before entry, reflecting a preference for candidates arriving with a fully developed clinical foundation who are committing specifically to laboratory-oriented medical genetics practice.